Clinical Trial

A Clinical Trial Comparing Low-Dose RT + Targeted Therapy+ Immunotherapy vs Targeted Therapy+ Immunotherapy Alone as Neoadjuvant Therapy in Operable HNSCC Patients.

Completed Phase 2
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Summary
This study aimed to compare the efficacy of neoadjuvant low-dose radiotherapy combined with targeted therapy and immunotherapy versus targeted therapy and immunotherapy alone in patients with resectable head and neck squamous cell carcinoma.
Protocol Amendment History 1 change
critical Trial completed 2026-07-01
Trial Details
NCT Number NCT07040956
Lead Sponsor West China Hospital
Conditions Head and Neck Squamous Cell Carcinoma, Low-dose Radiotherapy, Immunotherapy, Targeted Therapy
Enrollment 98 participants
Start Date 2025-06-28
Primary Completion 2026-06-26 (estimated)
Study Completion 2026-06-26 (estimated)
Updated on ClinicalTrials.gov 2026-06-30