Low-Flow Anesthesia and Open-Heart Surgery

Low-flow anesthesia (LFA) is a technique in which at least 50% of the exhaled air, after carbon dioxide absorption, is mixed with a certain amount of fresh gas and returned to the patient during the next inspiration. In 1974, R. Virtue defined minimal flow anesthesia (MFA) as 0.5 L/min. In 1984, Baker and Simionescu classified LFA as 0.5-1 L/min and MFA as 0.25-0.5 L/min. The aim of this study is to investigate whether there are hemodynamic differences between open-heart surgery cases performed with LFA at different fresh gas flow rates.

NCT Number	NCT07040735
Lead Sponsor	Çağrı Özdemir
Conditions	Low-flow Anesthesia, Hemodynamics, Open-heart Surgery
Enrollment	80 participants
Start Date	2025-07-01
Primary Completion	2026-09-02 (estimated)
Study Completion	2026-09-23 (estimated)
Updated on ClinicalTrials.gov	2026-05-27