Identification of Breast Cancer in Breath Samples Using Trained Detection Dogs

The goal of this study is to find out whether a system that uses trained detection dogs and artificial intelligence (AI) can identify breast cancer from a person's breath. Women who are scheduled to have routine breast cancer screening, such as a mammogram, ultrasound, or a biopsy for a possible cancer, will be invited to take part. Participants will be asked to breathe into a surgical mask to collect a breath sample. The mask will be sent to a special laboratory, where trained dogs and an AI-based system will check the sample for signs of breast cancer. The results from the dogs and AI will be compared to the actual results from the medical screening or biopsy to see how accurate the system is at detecting breast cancer.

NCT Number	NCT07038785
Lead Sponsor	SpotitEarly Collaborators: Hackensack Meridian Health, University of Pennsylvania
Conditions	Breast Cancer
Enrollment	1,204 participants
Start Date	2025-07-22
Primary Completion	2027-06 (estimated)
Study Completion	2027-06 (estimated)
Updated on ClinicalTrials.gov	2026-05-15