Clinical Trial

Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life

Study acronym: ProBUS
Recruiting
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Summary
Hip fractures often lead to functional limitations, loss of independence, weight loss and decreased well-being. Only half of the patients regain their functional level and 24% die within the following year. Financial consequences are significant due to costly surgery and long-term care. Hip fracture incidence is expected to increase sharply due to the ageing population, reducing accessibility to and quality of rehabilitation care. Therefore, optimizing treatment is essential. Previous protein and exercise studies showed improved muscle and bone health in healthy or frail community-dwelling older adults, but effects in older hip fracture patients are not known. Better rehabilitation may improve bone and muscle health, nutritional status, quality of life, lower costs and lower burden for healthcare. The overall objective is to investigate the effectiveness, costs and cost-effectiveness of a protein-enriched diet and resistance exercise for 3 months compared to usual care on bone and muscle health, and quality of life in older adults recovering from an acute hip fracture.
Trial Details
NCT Number NCT07036341
Lead Sponsor Wageningen University
Collaborators: Rijnstate Hospital, Gelderse Vallei Hospital, HAN University of Applied Sciences, Liemerije Revalidatiezorg, Opella Revalidatiezorg, Pleyade Revalidatiezorg, Attent Zorg en Behandeling, Alliantie Voeding in de Zorg, Osteoporosis Association
Conditions Hip Fractures
Enrollment 102 participants
Start Date 2024-09-01
Primary Completion 2026-08 (estimated)
Study Completion 2026-08 (estimated)
Updated on ClinicalTrials.gov 2025-06-25