University-Based Chagas Testing in Salta Province, Argentina

The goal of this observational study is to improve access to diagnosis and treatment for chronic Trypanosoma cruzi infection among university students of all ages and genders at the National University of Salta (UNSa), Argentina. The main questions it aims to answer are: * What is the seroprevalence and geographic distribution of T. cruzi infection in UNSa students? * Can voluntary point-of-care tests performed at university serve as an effective opportunity for timely diagnosis and linkage to care for Chagas disease? Participants will: 1. Be offered a RDTs (WL Check Chagas, Wiener Lab) during their regular activities in the university. 2. If RDT is positive, be referred to the health system for confirmatory testing and treatment. 3. Receive follow-up support by trained staff via phone. A subgroup of RDT-negative students will have serum samples preserved and analyzed later via ELISA to verify RDT accuracy.

NCT Number	NCT07033325
Lead Sponsor	Mundo Sano Foundation Collaborators: Universidad Nacional de Salta
Conditions	Chagas Disease, Trypanosoma Cruzi Infection, Chronic Chagas Disease
Enrollment	2,568 participants
Start Date	2024-09-11
Primary Completion	2025-08-31 (estimated)
Study Completion	2026-02-01 (estimated)
Updated on ClinicalTrials.gov	2026-06-23