Clinical Trial

Therapeutic Effect of Oral Hyaluronic Acid on Knee Osteoarthritis

Completed
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to investigate the effect of oral hyaluronate in patients with knee osteoarthritis. The main question it aims to answer is: the therapeutic effect in the combined treatment of oral nutritional supplement based on hyaluronic acid with hyaluronic acid intra-articular Injection on symptomatic knee osteoarthritis. Researchers will compare it to those who receive only hyaluronic acid injection to see if the combined treatment is better. Participants will receive a total of three months of oral hyaluronate or placebo agents.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-06-21.
Status change: Recruiting → Completed 2026-05-03
Trial Details
NCT Number NCT07033312
Lead Sponsor Taichung Veterans General Hospital
Conditions Knee Osteoarthritis
Enrollment 44 participants
Start Date 2023-04-21
Primary Completion 2025-02-17 (estimated)
Study Completion 2025-02-17 (estimated)
Updated on ClinicalTrials.gov 2026-05-07