YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study1

In order to reduce the clinical demand for kidney dialysis rate of Diabetic Kidney Disease（DKD） patients, a bidirectional cohort study of 4472 patients with DKD (Qi deficiency and collateral stasis syndrome) was carried out based on a preliminary DKD cohort of 13,000 patients. The exposure factor was supplementing and reducing the kidney turbidity-Huoxue Tongluo method represented by the addition and subversion of Shenzhuo prescription, and the incidence of end-stage renal disease was the main therapeutic index. Follow-up was conducted for 2 years

NCT Number	NCT07032116
Lead Sponsor	Liu Hongfang Collaborators: Guang'anmen Hospital of China Academy of Chinese Medical Sciences, First Affiliated Hospital, Sun Yat-Sen University, Tianjin Medical University, Changchun University of Chinese Medicine, EFONG PHARMRCEUTICRL, Xinxiang Central Hospital of Henan province, Xiamen Hospital of Traditional Chinese Medicine, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Beijing Tiantan Hospital, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine, Hubei Zhongshan Hospital Affiliated to Wuhan University
Conditions	Diabetic Kidney Disease (DKD)
Enrollment	4,472 participants
Start Date	2025-08-01
Primary Completion	2028-07-31 (estimated)
Study Completion	2028-07-31 (estimated)
Updated on ClinicalTrials.gov	2025-06-22