Clinical Trial

Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors.

Study acronym: ORGA-GLIO
Not Yet Recruiting
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Summary
The main goal of ORGA-GLIO trial is to establish the feasibility in routine clinical practice of ex-vivo organoid cultures composed of tumor cells within their microenvironment (glioblastoma organoid - GBO) and intra- and peri-tumoral blood vessels (blood vessel organoid - BVO), derived from perioperative samples obtained during complete or partial surgical resection in patients with newly diagnosed glioblastoma.
Trial Details
NCT Number NCT07029100
Lead Sponsor Centre Henri Becquerel
Conditions Glioblastoma
Enrollment 30 participants
Start Date 2025-07-01
Primary Completion 2027-07-01 (estimated)
Study Completion 2029-07-01 (estimated)
Updated on ClinicalTrials.gov 2025-06-19