Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07028476 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

New Care Pathway Using Automated Dynamic Laximetry

Study acronym: NPS-LDA
StatusRecruiting
PhaseNot applicable
Started2026-03-10
View on ClinicalTrials.gov ↗

Amendment history

2026-06-17
critical
Study Status, Outcome Measures, Contacts/Locations, IPDSharing v3
Primary endpoint(s) modified3 to 2 entries
WasEQ-5D-5L questionnaire, KOOS questionnaire, Tegner activity scale
NowEQ-5D-5L questionnaire, KOOS questionnaire
Secondary endpoints+224 characters
KOOS questionnaire Tegner activity scale Cost per QALY gained Time frame for therapeutic management Time to First Return to Sporting Activity Time to Return to Work Average recovery time to pre-sprain level: budgetary impact
Study sitesdetails revised at 2 of 3 sites
2026-03-10
notable
Not Yet Recruiting→Recruiting Study Status, Contacts/Locations v2
Trial statusNot Yet Recruiting→Recruiting
Primary completion date2027-02→2027-03
Completion date2028-02→2028-03
Start dateestimated 2026-02→confirmed 2026-03-10
Study sitesdetails revised at 3 of 3 sites
2026-02-13
minor
Study Status v1
Primary completion date2027-09-01→2027-02
Completion date2027-09-01→2028-02
Start date2025-09-01→2026-02
2025-06-11
minor
Original filing
Today, in the event of a knee sprain with suspected cruciate ligament damage, magnetic resonance imaging (MRI) is generally prescribed to confirm or refute the diagnosis and assess its severity. Once the MRI has been performed, the patient's care is organized by the doctor of his or her choice, depending on the diagnosis. Previous studies have shown that Automated Dynamic Laximetry (ADL) performs identically to MRI in helping to diagnose a knee sprain as a complementary examination and in assessing its severity. Performing LDA at the start of the patient's care pathway, i.e. immediately after the emergency room visit for a suspected severe sprain, could bring significant benefits by shortening the diagnostic confirmation time and consequently the immobilization period, and by reducing the cost of care compared with the conventional MRI-based care pathway. The new LDA-based care pathway would enable MRI to be reserved for very specific cases, such as the scheduling of surgery for suspected meniscus or osteochondral lesions, as currently recommended by the HAS.
Trial Details
NCT Number NCT07028476
Lead Sponsor University Hospital, Angers
Conditions Knee Sprain, Automated Dynamic Laximetry (ADL), Care Pathway, MRI
Enrollment 80 participants
Start Date 2026-03-10
Primary Completion 2027-03 (estimated)
Study Completion 2028-03 (estimated)
Updated on ClinicalTrials.gov 2026-06-18