Acute Treatment and Long-term Assessment of Adult Infectious Meningitis

Prospective, multicenter, observational clinical registry of adult patients with acute infectious meningitis across approximately 30 public and private hospitals in Brazil. The study will include adults, 18 years old and older, with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.

NCT Number	NCT07027475
Lead Sponsor	Hospital Israelita Albert Einstein Collaborators: Ministry of Health, Brazil
Conditions	Viral Meningitis, Bacterial Meningitis, Fungal Meningitis, Meningitis
Enrollment	624 participants
Start Date	2026-03-30
Primary Completion	2026-12 (estimated)
Study Completion	2027-02 (estimated)
Updated on ClinicalTrials.gov	2026-08-13