Feasibility, Safety and Effectivity of an Exercise Intervention for Newly Diagnosed Multiple Myeloma Patients During Induction Therapy

Physical exercise is an important supportive therapy for cancer patients, which improves quality of life and can effectively counteract the side effects of drug therapy. There is very little experience whether physical activity can also be performed safely by patients with malignant diseases that affect bone stability. This applies in particular to patients with multiple myeloma, a disease characterized by a monoclonal proliferation of plasma cells in the bone marrow and often accompanied by severe bony destruction. Aim of this exploratory randomized controlled trial is to evaluate feasibility, safety and effectivity of an orthopaedic-guided exercise intervention during induction therapy in newly diagnosed multiple myeloma patients.

NCT Number	NCT07026799
Lead Sponsor	University Hospital Heidelberg
Conditions	Multiple Myeloma Bone Lesions
Enrollment	50 participants
Start Date	2023-04-14
Primary Completion	2026-06-27 (estimated)
Study Completion	2026-06-27 (estimated)
Updated on ClinicalTrials.gov	2025-06-18