Clinical Trial

VA|PREVENTION: Randomized Controlled Trial of a Person-Centred Digital Intervention to Prevent Diabetes in High-Risk Adults

Study acronym: VA|PREVENTION
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to help prevent the development of type 2 diabetes (T2D) in adults who are at risk. The study will test a digital intervention called VA\|PREVENTION, a web application designed to support and promote healthy behaviour changes known has T2D risk factors, such as physical activity, diet, and sedentary behaviuor. The main questions this study will explore are:• Is the VA\|PREVENTION web app, which includes a virtual human coach, effective in preventing type 2 diabetes?• Can the VA\|PREVENTION web app be successfully implemented in real-world settings?• Is the VA\|PREVENTION web app cost-effective?• Is it safe for participants to use?To answer these questions, the study team will compare the VA\|PREVENTION web app to an openly available guidebook that provides standard information about preventing type 2 diabetes.Participants will complete the following activities: * Participants will be randomly assigned to one of two groups: one group will use the VA\|PREVENTION app, while the other group will have access to an openly accessible guidebook on T2D prevention. * Participants will be in the study for 10 months. * Participants will be assessed at the start of the study (baseline), and again at 4 months and 10 months. * Assessments will include body measurements (such as weight, height, and waist circumference), physical activity levels, and responses to questionnaires.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-06-06; most recent amendment 2026-02-18.
Status change: Recruiting → Active, Not Recruiting 2026-02-18
Trial Details
NCT Number NCT07021144
Lead Sponsor Egas Moniz - Cooperativa de Ensino Superior, CRL
Collaborators: Universidade Nova de Lisboa, FCiências.ID - Associação para a Investigação e Desenvolvimento de Ciências (Lisbon, Portugal), Nursing School of Lisbon, Faculdade de Motricidade Humana de Lisboa
Conditions Pre-diabetes, Pre-diabetic State
Enrollment 180 participants
Start Date 2025-06-03
Primary Completion 2026-11-16 (estimated)
Study Completion 2026-11-25 (estimated)
Updated on ClinicalTrials.gov 2026-02-19