Predicting Mortality in Patients With Return of Spontaneous Circulation After Cardiac Arrest

This retrospective observational cohort study aims to identify early predictors of short- and mid-term mortality in adult patients who achieved return of spontaneous circulation (ROSC) after cardiac arrest. Eligible patients admitted to the intensive care unit between January 1, 2024 and May 31, 2025 were identified retrospectively from electronic medical records following institutional ethics approval. Clinical, biochemical, and resuscitation-related parameters recorded within the first 24 hours of ICU admission were analyzed. The primary objective was to determine factors independently associated with short-term mortality. Six-month mortality was additionally assessed using hospital records and the national death registry. The findings are expected to improve risk stratification and clinical decision-making in post-cardiac arrest care.

NCT Number	NCT07020091
Lead Sponsor	Ahmet Düzgün
Conditions	Post-Resuscitation Syndrome, Critical Illness, Cardiac Arrest, Hypoxic-Ischemic Encephalopathy, Coma
Enrollment	168 participants
Start Date	2024-05-01
Primary Completion	2025-12-31 (estimated)
Study Completion	2025-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-05-08