Clinical Trial

Comparing PCCT With ICA and IVUS in Detecting Cardiac Allograft Vasculopathy

Study acronym: CAVIAR
Not Yet Recruiting
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Summary
In traditional coronary artery disease, patients often experience symptoms such as angina. However, heart transplant patients lack nerve connections in the transplanted heart and therefore usually do not notice any symptoms. For this reason, routine examinations are performed using traditional coronary angiography at one, three, and six years after transplantation, sometimes with the addition of coronary ultrasound. A new technique, photon-counting computed tomography, has now been developed and may potentially replace both traditional coronary angiography and intravascular ultrasound. In this study, we aim to investigate how well this method works in diagnosing coronary artery changes compared to the established methods.
Trial Details
NCT Number NCT07020039
Lead Sponsor Sahlgrenska University Hospital
Collaborators: Göteborg University
Conditions Cardiac Allograft Vasculopathy
Enrollment 100 participants
Start Date 2025-09-01
Primary Completion 2027-02-28 (estimated)
Study Completion 2027-08-31 (estimated)
Updated on ClinicalTrials.gov 2025-06-13