Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes

This study is testing whether a special form of magnesium called magnesium L-threonate can help improve sleep quality, recovery, and physical performance in college athletes. Magnesium is important for muscle recovery and sleep, but many forms of it do not enter the brain well. Magnesium L-threonate is unique in that it can cross the blood-brain barrier and may improve deep and REM sleep, heart rate variability, and brain recovery. In this study, healthy UCLA varsity athletes aged 18 to 35 will be randomly assigned to take either magnesium L-threonate or a placebo each evening for 4 weeks. They will wear a WHOOP strap to track sleep, recovery, and heart rate data. Performance tests including jump height, grip strength, and reaction time will be completed before and after the 4-week period. This study will help researchers determine if this supplement can support recovery and training in athletes and whether wearable technology can help monitor these changes in real time.

NCT Number	NCT07015047
Lead Sponsor	University of California, Los Angeles
Conditions	Recovery of Function (G11.427.698.620), Athletic Performance, Heart Rate Variability (HRV)
Enrollment	100 participants
Start Date	2025-10-01
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-07-15 (estimated)
Updated on ClinicalTrials.gov	2025-10-15