Comparison of Two Types of Radiofrequency Treatment for Trigeminal Neuralgia

Trigeminal neuralgia (TN) is a chronic pain condition that affects the face, often causing sharp, electric shock-like pain in areas served by the trigeminal nerve. When medications are no longer effective, interventional procedures such as radiofrequency ablation (RFA) may be used. This retrospective study compares two different RFA techniques in patients with classical TN: (1) conventional thermal RFA applied to the Gasserian ganglion, and (2) pulsed RFA applied peripherally to the nerve branches. The purpose of the study is to evaluate pain relief, patient satisfaction, and complication rates between these two commonly used techniques. A total of 60 patients aged 55-80 years, who were treated at the Mersin University Pain Clinic between January 2015 and June 2025, were included. The study uses clinical records and follow-up data to assess outcomes at 6 months post-procedure. This study aims to provide clinicians with more evidence to guide the selection of safer and more effective treatments for trigeminal neuralgia, with the goal of improving patients' quality of life and reducing treatment-related side effects.

NCT Number	NCT07013500
Lead Sponsor	Mesut Bakır
Conditions	Trigeminal Neuralgia, Tic Douloureux, Neuropathic Facial Pain
Enrollment	60 participants
Start Date	2025-06-15
Primary Completion	2025-07-01 (estimated)
Study Completion	2025-07-30 (estimated)
Updated on ClinicalTrials.gov	2025-06-10