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A EUROpean Randomized Study on Blood-thinners and Cholesterol-lowering Treatments to Prevent Future Vascular Events in People With Covert Brain Infarcts (CBI)

Study acronym: EURO-CBI
StatusRecruiting
PhasePhase 3
Started
View on ClinicalTrials.gov ↗

Record History

  1. Notable Trial status: Not Yet Recruiting to Recruiting Start date changed from estimate of Sep 1, 2025 to Nov 26, 2025 · Site details revised at 14 of 14 sitesv2 Show 2 more changesShow less
    • Start date changed from estimate of Sep 1, 2025 to Nov 26, 2025
    • Site details revised at 14 of 14 sites
  2. Minor Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Magnetic resonance imaging (MRI) is commonly used in healthcare, and sometimes it shows small areas of brain damage called Covert Brain Infarcts (CBIs). These are usually found by chance when people have scans for things like headaches or dizziness. Although CBIs don't cause symptoms at the time, they are linked to a higher risk of future stroke and death. There is currently no standard treatment for CBIs, and doctors have different approaches-some give stroke-preventing medication (like antiplatelets or statins), while others don't treat at all. This is mostly because there isn't enough research yet. This study will test whether stroke-preventing treatments help people with CBIs. It will also look at whether having a CBI increases the risk of dementia, and whether treatment might lower that risk.
Trial Details
NCT Number NCT07012629
Lead Sponsor Aarhus University Hospital
Collaborators: Rigshospitalet, Denmark, Bispebjerg Hospital, Herlev Hospital, Zealand University Hospital, Odense University Hospital, Aalborg University Hospital, Gødstrup Hospital, Oslo University Hospital, Universitätsklinikum Hamburg-Eppendorf, Insel Gruppe AG, University Hospital Bern, Lund University Hospital
Conditions Covert Brain Infarction
Enrollment 1,652 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov