Clinical Trial

Adjusted Study Protocol: Within-Subject Paired-Eye Design Comparing Pilocarpine 0.1%, Phentolamine 0.75%, and Combination Therapy for Cyclopentolate Reversal in Children

Not Yet Recruiting
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Record status
This record was last updated June 10, 2025 (before its estimated December 1, 2025 completion). Its status may not reflect the trial's current state.
Summary
The study aims at reversing pupillary dilatation. and cycloplegia in children undergoing cycloplegic refraction for eyeglasses prescription and ocular examination. This will be achieved using pilocarpine , phentolamine or a combination. This may help decrease the glare and improve near vision early to decrease unwanted effects of cycloplegic drops.
Trial Details
NCT Number NCT07012512
Lead Sponsor Mansoura University
Conditions Pupillary Constriction, Accomodation
Enrollment 60 participants
Start Date 2025-06-01
Primary Completion 2025-12-01 (estimated)
Study Completion 2025-12-30 (estimated)
Updated on ClinicalTrials.gov 2025-06-10