Clinical Trial

A Clinical Trial of CAP-003 Gene Therapy in Adult Patients With GBA1 Associated Parkinson's Disease

Withdrawn Phase 1/2
View on ClinicalTrials.gov →
Why the trial stopped
Per protocol stopping rule was met for a separate trial for a different disease state and different experimental therapy that utilized a similar technology.
Summary
The goal of this clinical trial is to learn about the safety of CAP-003 gene therapy in adults with GBA1 associated Parkinson's Disease. It will also provide information about whether CAP-003 demonstrates efficacy in these adults. Participants will have a single intravenous infusion of CAP-003 and visit the clinic regularly for 2 years for checkups and tests.
Protocol Amendment History 8 amendments
This ClinicalTrials.gov record has been amended 8 times since 2025-06-02; most recent amendment 2026-06-18.
Status change: Suspended → Withdrawn 2026-06-18
Status change: Recruiting → Suspended 2025-09-23
Status change: Not Yet Recruiting → Recruiting 2025-08-14
Trial Details
NCT Number NCT07011771
Lead Sponsor Capsida Biotherapeutics, Inc.
Conditions GBA1 Parkinson Disease
Start Date 2025-08-18
Primary Completion 2026-06-17 (estimated)
Study Completion 2026-06-17 (estimated)
Updated on ClinicalTrials.gov 2026-06-22