Effects of Ropivacaine Concentrations on Prolonged Labor Analgesia

With the changes in medical models and improvements in people's quality of life, parturients have higher demands for childbirth, making the alleviation and elimination of labor pain an important aspect of modern obstetrics. Intrathecal labor analgesia has been widely adopted in clinical practice to relieve pain. However, current studies mainly focus on parturients who are just beginning to receive labor analgesia, while for those experiencing prolonged analgesia, medical institutions still use traditional formulations, lacking relevant guidelines or expert consensus. In such cases, prolonged waiting and anxiety may lower the pain tolerance of parturients, leading to an increased need for higher concentrations of local anesthetics. To address this clinical gap, this study aims to explore the effects of different concentrations of ropivacaine in prolonged labor analgesia and has designed a prospective randomized controlled trial (RCT) to provide evidence for improving the analgesic regimen for this group of parturients.

NCT Number	NCT07007650
Lead Sponsor	Chengdu Jinjiang Maternity and Child Health Hospital
Conditions	Labor Analgesia, Prolonged, Ropivacaine, Concentration
Enrollment	100 participants
Start Date	2025-06-14
Primary Completion	2025-08-01 (estimated)
Study Completion	2025-09-10 (estimated)
Updated on ClinicalTrials.gov	2025-06-06