Clinical Trial

Swallowing Impairments in ICU Survivors and Community-Dwelling Adults

Withdrawn
View on ClinicalTrials.gov →
Why the trial stopped
Change of scope of the work given feedback from funding agency leading to new IRB/clinicaltrials.gov registration.
Summary
Post-intensive care syndrome (PICS), which consists of physical, cognitive, and psychosocial problems, is a pervasive complication for older intensive care unit (ICU) survivors and contributes to detrimental health outcomes and significant reductions in quality of life. Yet, little is known about the relationship between PICS, swallowing difficulties (dysphagia), and other ICU-related negative outcomes such as frailty and Alzheimer's Disease and Related Dementias (ADRD). The primary purpose of this research study is to determine the prevalence and severity of dysphagia, risk factors for dysphagia development, recovery patterns of dysphagia over time, and the impact of dysphagia on health outcomes, quality of life, and care partner burden in adult ICU survivors with PICS.
Protocol Amendment History 3 changes
critical Trial status changed: Not Yet Recruiting → Withdrawn 2026-06-03
critical Reason stopped changed: — → Change of scope of the work given feedback from funding agency leading to new IRB/clinicaltrials.gov registration. 2026-06-03
notable Enrollment reduced: 460 -> 0 participants 2026-06-03
Trial Details
NCT Number NCT07005037
Lead Sponsor Vanderbilt University Medical Center
Conditions Dysphagia, Healthy Aging, Post Intensive Care Syndrome, Caregiver Burden
Start Date 2027-04-01
Primary Completion 2029-07-30 (estimated)
Study Completion 2030-07-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-02