Clinical Trial

Proving Utility of a New Field-cycling MRI Prototype in Acute Stroke Patients

Study acronym: PUFFINS 3

Recruiting

Record status

This record was last updated January 27, 2026 (before its estimated May 2026 completion). Its status may not reflect the trial's current state.

Summary

The goal of this study is to test if a new type of MRI scanner, called Field-Cycling Imaging (FCI), can show changes in the brain within the first day of a stroke due to a blocked blood vessel or bleeding in the brain. The main question it aims to answer is: • Can FCI identify brain tissue that might recover within the first few hours after a stroke begins? Participants will undergo a standard MRI scan and an FCI scan, as soon as possible after hospital admission. Participants who have had a blocked blood vessel will also provide a blood sample and will have a follow up visit at 30 days for repeat of both scans and providing another blood sample.

Protocol Amendment History 1 amendment

This ClinicalTrials.gov record has been amended once since 2025-05-26.

Status change: Not Yet Recruiting → Recruiting 2026-01-26

Trial Details

NCT Number	NCT07004140
Lead Sponsor	University of Aberdeen Collaborators: NHS Grampian
Conditions	Stroke Acute
Enrollment	40 participants
Start Date	2025-09-16
Primary Completion	2026-05 (estimated)
Study Completion	2026-05 (estimated)
Updated on ClinicalTrials.gov	2026-01-27