Clinical Trial

Wide-Awake Local Anesthesia No Tourniquet (WALANT) With Versus Without Hyaluronidase for Hand Surgery

Active, Not Recruiting Phase 2/3
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Record status
This record was last updated July 29, 2025 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.
Summary
The WALANT (Wide Awake Local Anesthesia No Tourniquet) method, introduced by Dr. Donald H. Lalonde over a decade ago, has gained popularity due to its favorable outcomes and patient satisfaction. This technique involves injecting diluted lidocaine and epinephrine, which helps control pain and bleeding without the discomfort of a tourniquet. This research will explore the use of hyaluronidase to enhance the WALANT technique. The study hypothesize that adding hyaluronidase would improve the onset speed and duration of pain control. A double-blinded study involving 100 patients compared WALANT with hyaluronidase (Group A) to WALANT without Hyaluronidase (Group B).
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-05-23; most recent amendment 2025-07-24.
Status change: Recruiting → Active, Not Recruiting 2025-07-24
Trial Details
NCT Number NCT07000058
Lead Sponsor Misr University for Science and Technology
Conditions Hand Surgery, Local Infiltration
Enrollment 100 participants
Start Date 2025-06-20
Primary Completion 2025-12-31 (estimated)
Study Completion 2025-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-07-29