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Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73

Name: Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73 — clinical trial record (NCT06995976)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

StatusRecruiting

PhaseEarly Phase 1

SponsorFirst Affiliated Hospital of Fujian Medical University

Started2025-03-01

View on ClinicalTrials.gov ↗

Record status

This record was last updated May 30, 2025 (before its estimated December 31, 2025 completion). Its status may not reflect the trial's current state.

First Affiliated Hospital of Fujian Medical University

56 trials monitored

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As a new CD73-targeted PET radiotracer, 68Ga-dPNE, is promising as an excellent imaging agent applicable to various cancers. In this study, we observed the safety, biodistribution and radiation dosimetry of 68Ga-dPNE in human volunteers. Furthermover, we conducted a comparative analysis of 68Ga-dPNE and 18F-FDG imaging to assess both the radiation dosimetry and diagnostic efficacy of 68Ga-dPNE.

Trial Details

NCT Number	NCT06995976
Lead Sponsor	First Affiliated Hospital of Fujian Medical University
Conditions	Malignant Tumour
Enrollment	30 participants
Start Date	2025-03-01
Primary Completion	2025-12-31 (estimated)
Study Completion	2026-03-01 (estimated)
Updated on ClinicalTrials.gov	2025-05-30