Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is critical for multi-tasking in daily life. The proposed research investigates whether playing a web-based cognitive complex game (the Breakfast Game) impacts cognitive performance in cognitively healthy older adults. To be enrolled in the study, participants will be asked to undergo a cognitive sassessment, health questionnires, and a blood exam. The intervention consist in one educational session on healthy aging, and 10 one-hour cognitive training sessions 2-3 times a week over one month. Participants will be asked to repeat the cognitive assessment within 1-2 weeks after the intervention, and after three months.

NCT Number	NCT06995638
Lead Sponsor	Rutgers, The State University of New Jersey Collaborators: National Institute on Aging (NIA)
Conditions	Healthy Aging, Alzheimer's Disease (AD)
Enrollment	130 participants
Start Date	2025-12-10
Primary Completion	2027-12 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2025-12-15