Map of Tumor Genetic Actionability in Argentina

The study of the human genome laid the foundations for the search for a large number of molecular alterations related to different diseases. The Precision medicine allows us to know molecular alterations that can be detected and targeted for therapeutic purposes. There is little data in Argentina about the incidence and frequencies of alterations molecules associated with the most frequent tumors. Through the selection of a gene panel, analysis of the genetic information obtained analysis allows classifying tumors from a point of view therapeutic. On the other hand, through the same panel, markers of resistance to drugs that allow the incorporation of retreatment therapies. Together with the proposed panel, the ancestry of the patients will be evaluated to determine whether the frequencies of molecular alterations vary between the different ethnic origins of the country.

NCT Number	NCT06995235
Lead Sponsor	Hospital Italiano de Buenos Aires
Conditions	Neoplasms Malignant, Biomarkers
Enrollment	100 participants
Start Date	2024-04-01
Primary Completion	2025-12 (estimated)
Study Completion	2026-04-22 (estimated)
Updated on ClinicalTrials.gov	2025-05-29