Clinical Trial

Labor Education to Reduce Postpartum Traumatic Stress

Study acronym: LEPT
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
The goal of this randomized controlled trial is determine if education on common events in labor in nulliparous women can reduce the postpartum traumatic symptoms. The main question it aims to answer are: * Does prenatal education on labor events reduce post-traumatic symptoms, as measured by thePost Traumatic Stress Disorder Cecklist for Diagnostic and Statistical Manual for Mental Health Disorders (PCL-5) at 6 weeks postpartum? * Does prenatal education on labor affect labor outcomes? Participants will be given surveys: * At enrollment on mental health and previous traumatic experiences * After education on expectations on childbirth * After delivery on experience of childbirth * At 6 weeks and 6 months postpartum on traumatic symptoms and mental health outcomes. They will also have the option to participate in collection of discarded cerebrospinal fluid, blood and serum and physiologic sensitivity testing.
Protocol Amendment History 3 amendments
This ClinicalTrials.gov record has been amended 3 times since 2025-05-19; most recent amendment 2026-06-19.
Status change: Enrolling by Invitation → Active, Not Recruiting 2026-06-19
Status change: Not Yet Recruiting → Enrolling by Invitation 2025-11-12
Trial Details
NCT Number NCT06992791
Lead Sponsor University of California, San Diego
Conditions Postpartum Complication, Posttraumatic Stress Symptoms
Enrollment 400 participants
Start Date 2025-10-14
Primary Completion 2026-10-15 (estimated)
Study Completion 2027-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-06-23