Clinical Trial

Clinical Trial for the Comparative Evaluation of Acid Suppression and Symptom Management of Gastroesophageal Reflux Disease With the Administration of Tegoprazan or Pantoprazole

Study acronym: TOP-GERD
Recruiting Phase 4
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Record status
This record was last updated July 23, 2025 (before its estimated November 30, 2025 completion). Its status may not reflect the trial's current state.
Summary
The objective of this clinical trial is to compare which of the two drugs best resolves symptoms in patients diagnosed with erosive and non-erosive gastroesophageal reflux disease, adult males and females. The main question is What is the proportion of patients with resolution of the main symptoms of gastroesophageal reflux disease at four weeks of treatment with pantoprazole vs tegoprazan.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-05-20.
Trial Details
NCT Number NCT06991348
Lead Sponsor Carnot Laboratories
Conditions Gastroesophageal Reflux Disease
Enrollment 128 participants
Start Date 2024-07-30
Primary Completion 2025-11-30 (estimated)
Study Completion 2025-11-30 (estimated)
Updated on ClinicalTrials.gov 2025-07-23