Effects of Orthosis & Exercise on Spondylolisthesis

In the treatment of spondylolisthesis, conservative methods are initially preferred unless severe neurological symptoms are present; surgical treatment is only performed in refractory cases lasting at least 3-6 months. Conservative treatment consists of orthotic use, activity restriction, pain control, physiotherapy and exercise. Orthotics may promote healing by restricting movement; however, there are not enough studies on this subject. Exercise is the intervention with the highest level of evidence in chronic low back pain. The efficacy of stabilisation exercises in providing positive and long-lasting effects on pain and functional disability in patients with spondylolisthesis has been demonstrated. However, studies evaluating the effect of exercise on spinal stability and radiological findings are limited. Therefore, this study aims to compare the effects of stabilization and conventional exercises with orthosis on radiographic findings, pain, physical function and quality of life.

NCT Number	NCT06989138
Lead Sponsor	Medipol University Collaborators: Baltalimani Bone Diseases Research and Training Hospital
Conditions	Spondylolisthesis, Orthosis, Exercise Training
Enrollment	48 participants
Start Date	2025-07-26
Primary Completion	2026-11 (estimated)
Study Completion	2027-02 (estimated)
Updated on ClinicalTrials.gov	2026-08-03