Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT06988020 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

"Pseudo-scanner" MRI Sequences for the Detection of Bone Lesions in Multiple Myeloma

Study acronym: MM-ZTE-II
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗

Record History

See every version on ClinicalTrials.gov ↗

  1. Trial status: Not Yet Recruiting to Recruiting
    • Study sites: 2 to 1
    • Start date changed from estimate of Jun 2025 to Apr 22, 2025
    v3
  2. Study title shortened, about 13 wordsv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
Recent work has confirmed the diagnostic performance of pseudo-CT sequences for detecting osteolytic lesions. Their integration into whole body MRI (WB MRI) could transform the diagnostic approach to MM, by allowing a combined assessment of bone marrow involvement, tissue viability and osteolysis, during a single non-irradiating imaging examination. Since the preliminary work mentioned above, optimizations have been made to the pseudo-CT sequences, including the addition of deep learning (correcting noise in the images) and the correction of chemical shift artifact (linked to the coexistence of hydrated tissue and fatty tissue), which carry real hope of improving their diagnostic potential and accuracy.
Trial Details
NCT Number NCT06988020
Lead Sponsor Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Collaborators: General Electric
Conditions
(from sponsor)		 Multiple Myeloma Bone Disease
Related terms Multiple Myeloma
Enrollment 45 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov