Clinical Trial

Gastric Emptying in Healthy Volunteers and GLP-1 Agonist Users

Study acronym: aGLP1-GUS
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Summary
This observational study aims to determine the gastric emptying kinetics assessed by ultrasound in healthy volunteers after a standard breakfast and the state of the stomach after a clear liquid diet for 18 /24 hours in patients on GLP-1 agonist. The main questions it seeks to answer are: * Is the kinetic after a standard breakfast that includes ( avocado and eggs: high fat) as fast as a standard meal that does not involve this food? * Is a clear liquid diet of 18 to 24 hours enough to be an empty-stomach, assessed by Ultrasound in patients on GLP1 agonist? Participants will be asked to do: -A baseline Gastric US will be performed for healthy volunteers, and then they will have a standardized breakfast. An hourly or bihourly assessment will be done by the US.
Trial Details
NCT Number NCT06987669
Lead Sponsor Clinica Alemana de Santiago
Conditions Diabetes Type 2, Obesity and Overweight
Enrollment 155 participants
Start Date 2025-05-17
Primary Completion 2026-12-31 (estimated)
Study Completion 2027-12-31 (estimated)
Updated on ClinicalTrials.gov 2025-05-23