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tdCS Combined With Treadmill Training in Patients With Multiple Sclerosis

Study acronym: TDCS
StatusRecruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Record status
This record was last updated May 29, 2025 (before its estimated August 31, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Trial status: Enrolling by Invitation to Recruiting
    • Study sites: 1 to 2
    • Start date: May 15, 2025 to May 26, 2025
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This clinical trial aims to evaluate the therapeutic effectiveness of transcranial direct current stimulation (tDCS), a non-invasive technique that modulates cortical excitability, in combination with gait training in patients with multiple sclerosis (MS). The study focuses on improving balance and walking ability, which are commonly impaired in this population. A randomized, triple-blind, controlled design will be used, comparing an active tDCS group with a sham stimulation group, both receiving the same gait training protocol. Outcomes will include functional and clinical measures related to mobility, balance, and fatigue. The project builds on previous meta-analytical evidence suggesting positive effects of tDCS in MS and aims to confirm these findings using an optimized stimulation protocol.
Trial Details
NCT Number NCT06986278
Lead Sponsor University of Castilla-La Mancha
Collaborators: Asociación Esclerosis Múltiple de Toledo, España
Conditions
(from sponsor)		 tDCS, Sham tDCS
Related terms Multiple Sclerosis
Enrollment 78 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov