The Effect of Neoadjuvant Chemotherapy on Physical Functions

The aim of this observational study was to investigate the effect of neoadjuvant chemotherapy on physical functioning in individuals with breast cancer. The main question that the study aims to answer is how the physical functions of individuals are after neoadjuvant chemotherapy. Demographic information of the participants will be recorded and their physical status will be evaluated by determining body weight and composition, 30-second sit-and-stand test, 9-step stair ascent and descent test, one-leg stand test, upper extremity muscle strength test, lower extremity muscle strength test, tissue dielectric constant measurement, Lower Extremity Functional Scale, Global Physical Activity Questionnaire and Multidimensional Fatigue Rating Scale. In these patients who are planned to receive neoadjuvant chemotherapy for breast cancer, measurements will be made before chemotherapy (T1) and after chemotherapy (T2).

NCT Number	NCT06986005
Lead Sponsor	ATİYE KAŞ ÖZDEMİR
Conditions	Breast Cancer, Neoadjuvant Chemotherapy, Neoadjuvant Therapy
Enrollment	67 participants
Start Date	2025-01-08
Primary Completion	2025-07-10 (estimated)
Study Completion	2025-11-15 (estimated)
Updated on ClinicalTrials.gov	2026-02-20