Clinical Trial

The Effect of the Menstrual Cycle on Immune Cell Activity and Recovery After Resistance Exercise

Recruiting
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Summary
The goal of this observational study is to learn how the menstrual cycle affects immune cell activation, recruitment, and recovery responses after resistance exercise in healthy, resistance-trained women aged 18-40. The main questions it aims to answer are: Does the menstrual cycle influence neutrophil recruitment and adhesion after resistance exercise? Does the menstrual cycle affect markers of muscle damage and functional recovery? Researchers will compare three menstrual phases (early follicular, late follicular, and mid-luteal) to see if immune responses and recovery outcomes differ across these phases. Participants will: Complete resistance exercise protocols across three different menstrual cycle phases. Provide blood samples to assess immune cell activation and muscle damage markers. Track sleep, mood, and recovery with questionnaires and wear an accelerometer.
Trial Details
NCT Number NCT06985420
Lead Sponsor University of Central Florida
Conditions Healthy Women, Menstruation, Resistance Exercise
Enrollment 40 participants
Start Date 2024-08-16
Primary Completion 2025-05 (estimated)
Study Completion 2025-05 (estimated)
Updated on ClinicalTrials.gov 2025-05-22