Clinical Trial

4-day Plaque Accumulation Model Evaluating Compound Containing Gum

Recruiting
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Record status
This record was last updated August 27, 2025 (before its estimated January 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This will be a single-blind, single-center, 3-way crossover, randomized controlled clinical trial with 3 treatment periods utilizing 32 subjects. (Fig 1, in protocol) Each treatment period will be 4 days (96 hours +/-3 hours) in accordance with the plaque accumulation model using one of the following treatment groups: an active compound MIIP-E2 gum (experimental regimen), an inactive compound gum (negative control regimen), and a no-gum (control regimen).
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-05-14; most recent amendment 2025-08-26.
Status change: Not Yet Recruiting → Recruiting 2025-08-26
Trial Details
NCT Number NCT06984744
Lead Sponsor Lactea Therapeutics, LLC
Collaborators: Indiana University
Conditions Dental Plaque Accumulation
Enrollment 32 participants
Start Date 2025-06-23
Primary Completion 2026-01-30 (estimated)
Study Completion 2026-02-27 (estimated)
Updated on ClinicalTrials.gov 2025-08-27