Clinical Trial

MRONJ and Polynucleotides-Hyaluronic Acid Hydrogel (Regenfast®)

Study acronym: REG-MRONJ-1
Not Yet Recruiting
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Summary
Several circumstances or conditions, such as wound extension or disease, can affect the hard and soft tissue healing after surgical treatment of MRONJ. Supportive therapies are therefore needed to help tissues wound healing. The primary objective of this pilot clinical case series is to evaluate the post-operative wound healing in a group of patients undergoing surgical therapy for MRONJ with intraoperative application of a gel based on polynucleotides and hyaluronic acid (PN+HA) (Regenfast®)
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-05-20.
Trial Details
NCT Number NCT06984107
Lead Sponsor Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Conditions Medication Related Osteonecrosis of the Jaw
Enrollment 10 participants
Start Date 2025-09-01
Primary Completion 2026-09-01 (estimated)
Study Completion 2027-03-01 (estimated)
Updated on ClinicalTrials.gov 2025-05-29