Clinical Trial

This Study Will Evaluate the Safety and Potential Complications of Dual ProGlide vs Single ProGlide and Angioseal for Common Femoral Arteriotomy Closure Following Transcatheter Aortic Valve Replacement

Study acronym: TAVI-CLOSE
Completed
View on ClinicalTrials.gov →
Summary
This prospective, randomized, parallel, single-center, open-label, non-inferiority study will evaluate the safety and potential complications of dual ProGlide vs single ProGlide and Angioseal for common femoral arteriotomy closure following Transcatheter Aortic Valve Replacement.
Protocol Amendment History 6 amendments
This ClinicalTrials.gov record has been amended 6 times since 2025-05-14; most recent amendment 2026-06-01.
Status change: Active, Not Recruiting → Completed 2025-11-20
Status change: Recruiting → Active, Not Recruiting 2025-09-16
Trial Details
NCT Number NCT06983938
Lead Sponsor Baylor Research Institute
Conditions Transcatheter Aortic Valve Replacement, Closure Technique
Enrollment 92 participants
Start Date 2025-02-12
Primary Completion 2025-08-13 (estimated)
Study Completion 2025-10-15 (estimated)
Updated on ClinicalTrials.gov 2026-06-25