Clinical Trial

The Effect of Local Infiltration of Tranexamic Acid on Postoperative Blood Loss in Orthognathic Surgery

Not Yet Recruiting Phase 1/2
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Record status
This record was last updated May 21, 2025 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
The effect of local infiltration of tranexamic acid in orthognathic surgery remains unclear. This study was conducted to evaluate the difference in postoperative blood loss, measured by surgical drain output, following orthognathic surgery. The investigation involved a within-subject comparison, where each side of the mandible received a different local anesthetic solution: one side was infiltrated with a mixture of lidocaine with adrenaline and tranexamic acid, while the other side received lidocaine with adrenaline and normal saline.
Trial Details
NCT Number NCT06983886
Lead Sponsor Ramathibodi Hospital
Conditions Postoperative Blood Loss in Patient Undergoing Orthognathic Surgery
Enrollment 25 participants
Start Date 2025-05-12
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-09-30 (estimated)
Updated on ClinicalTrials.gov 2025-05-21