Clinical Trial

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

Recruiting Early Phase 1
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Summary
The goal of this clinical trial is to learn about the processes occurring in the kidneys while under heat stress in healthy volunteers. The main questions it aims to answer are: * How do the chemicals produced by the body change under conditions of higher versus lower heat stress? * What role does a specific area of the body's metabolism, known as NAD+ metabolism, play in the body's response to heat stress, and can this response be modified by taking vitamin B3?
Protocol Amendment History 5 amendments
This ClinicalTrials.gov record has been amended 5 times since 2025-05-14; most recent amendment 2026-02-03.
Status change: Not Yet Recruiting → Recruiting 2026-02-03
Trial Details
NCT Number NCT06983730
Lead Sponsor Beth Israel Deaconess Medical Center
Collaborators: Boston University Charles River Campus, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions Heat Strain, Healthy Volunteer Study, Kidney Dysfunction
Enrollment 28 participants
Start Date 2026-01-26
Primary Completion 2028-06 (estimated)
Study Completion 2028-06 (estimated)
Updated on ClinicalTrials.gov 2026-02-05