Structural Heat Adaptation and Education in Rural Setting

This study aims to understand whether simple, low-cost interventions, such as improved home cooling, practical advice, and minor home modifications, can help protect people's health and quality of life during periods of extreme heat in rural, low-income villages of Matiari, Pakistan. Key Questions the Study Seeks to Answer: 1. Can these interventions reduce heat-related health problems such as dizziness, headaches, and heatstroke and improve quality of life? 2. Can they lower indoor temperatures and improve sleep quality, comfort, and daily functioning? To answer these questions, researchers will compare communities where families receive heat-related support and information with similar communities that do not, to assess any differences in health and well-being. Endline venous blood sampling will be conducted for biobanking only. What Participants Can Expect: * Answer questions about their health, living conditions, and how they cope with heat * Have small temperature sensors placed inside their homes * Some participants may wear a lightweight wristband that tracks sleep and heart rate * In selected households, cooling improvements will be made, such as adding shade, applying reflective roof paint, or enhancing airflow Purpose: This study seeks to identify affordable and effective strategies to help families stay safe during extreme heat, and to use these insights to support other vulnerable communities facing similar challenges.

NCT Number	NCT06983483
Lead Sponsor	Aga Khan University Collaborators: London School of Hygiene and Tropical Medicine, University College, London
Conditions	Heat Illness, Quality of Life
Enrollment	7,128 participants
Start Date	2026-01-01
Primary Completion	2027-12-31 (estimated)
Study Completion	2028-02 (estimated)
Updated on ClinicalTrials.gov	2026-06-25