Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases

This upcoming case-control study aims to confirm the Lung Sliding Index (LSI), a new ultrasound score that measures how well the pleura moves, in various lung diseases. The study will check how well the LSI can tell apart different lung diseases (like pneumothorax, interstitial lung disease, COPD, pneumonia, and pulmonary edema), how it relates to signs of disease severity, and how consistent the results are between different operators who have received the same training. Secondary objectives include assessing patient and operator satisfaction and feasibility using validated Likert scales.

NCT Number	NCT06983366
Lead Sponsor	Assiut University Collaborators: Aliae AR Mohamed Hussein [ahussein
Conditions	COPD, ILD, Bronchiectasis, Pneumothorax, Pneumonia, Pleural Effusion Disorder, Pulmonary Oedema
Enrollment	700 participants
Start Date	2025-05-30
Primary Completion	2026-07-01 (estimated)
Study Completion	2026-08-01 (estimated)
Updated on ClinicalTrials.gov	2026-04-30