Efficacy of Trazodone to Treat Insomnia in Older Adults (TRADITION Study)

This study aims to evaluate how effective trazodone is in treating insomnia in adults aged 65 years and older. The main question it aims to answer is : \- Is trazodone more effective than a placebo in reducing the severity of insomnia symptoms in older adults? Participants will : * Take 25 to 50 mg of trazodone or a matching placebo before bed for 28 days. After a 2-week break, they will then take the other medication for another 28 days. * Visit the clinic three times for checkup and test * Complete a sleep diary and wear an actimeter during the night.

NCT Number	NCT06983080
Lead Sponsor	Centre hospitalier de l'Université de Montréal (CHUM)
Conditions	Insomnia Chronic, Older People, Drug Therapy
Enrollment	40 participants
Start Date	2025-11-10
Primary Completion	2027-07 (estimated)
Study Completion	2027-12 (estimated)
Updated on ClinicalTrials.gov	2025-12-08