Clinical Trial

STN-tTIS Modulates Parkinson Motor Symptoms With and Without Medications

Enrolling by Invitation
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Summary
The goal of this clinical trial is to evaluate the immediate effects of individualized 130 Hz STN-tTIS(Subthalamic Nucleus - transcranial Temporal Interference Stimulation)on motor symptoms in early-to-mid-stage PD patients during both medication "on" and "off" states. The main questions it aims to answer are: 1. Does the therapeutic effect of STN - tTIS relate to medication? 2. The degree of improvement in motor symptoms of Parkinson's disease patients after STN - tTIS therapy under different medication conditions. Researchers compared the MDS - UPDRS - III improvement scores of tTIS therapy in the "on" and "off" medication phases to see if tTIS could work of independently medication. 1. Visit the clinic once every 1 weeks for therapy and test. 2. Record their symptoms and scores.
Trial Details
NCT Number NCT06980935
Lead Sponsor Ruijin Hospital
Conditions Parkinson Disease
Enrollment 20 participants
Start Date 2025-04-14
Primary Completion 2025-05-15 (estimated)
Study Completion 2025-05-18 (estimated)
Updated on ClinicalTrials.gov 2025-05-20