Clinical Trial

The PROTECT Trial: PROpofol Titration to Enhance haemodynamiC sTability

Recruiting
View on ClinicalTrials.gov →
Summary
The aim of this multicentre, single-blinded, expertise-based randomised controlled trial is evaluate whether slowly increasing the dose of the anaesthetic drug propofol based on a patient's needs leads to more stable blood pressure compared to giving a standard starting dose in patients aged 55 and older undergoing non-cardiac surgery.
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-05-16; most recent amendment 2025-09-12.
Status change: Not Yet Recruiting → Recruiting 2025-09-12
Trial Details
NCT Number NCT06980688
Lead Sponsor University Hospital, Basel, Switzerland
Collaborators: University of Basel, University of Zurich
Conditions Anesthesia
Enrollment 320 participants
Start Date 2025-09-02
Primary Completion 2027-09 (estimated)
Study Completion 2027-09 (estimated)
Updated on ClinicalTrials.gov 2025-09-19