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HYEEG Discourse in Psychosis: A Neurobehavioural Study

Study acronym: DISCOURSE-NB
StatusRecruiting
PhaseNot specified
Started
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Record status
This record was last updated May 18, 2025 (before its estimated October 22, 2025 completion). Its status may not reflect the trial's current state.

Record History

  1. Minor Study First Submitted
This multimodal study explores the mechanisms underlying social dysfunction in individuals with schizophrenia. It focuses on the relationship between disorganized communication and social interaction, aiming to identify measurable markers of disorganized communication and link them to clinical symptoms and social functioning. Key Research Questions: How do neural and behavioural synchrony contribute to social impairments in schizophrenia? What roles do interbrain synchrony, motor imitation, reaction time, and verbal coherence play in disorganized communication? Participants will: 1. Engage in structured and semi-structured real-time social interactions while undergoing dual-brain electroencephalogram (EEG) hyperscanning to measure neural and behavioural activity. 2. Perform nonverbal tasks such as motor imitation and reaction time assessments to investigate coordination and behavioural synchrony patterns. 3. Participate in a clinical interview that evaluates verbal production, thought coherence, and speech organization. By combining these assessments, the study aims to advance our understanding of how social and communication impairments manifest in schizophrenia. The findings will contribute to developing improved diagnostic tools and targeted interventions, ultimately supporting patients in achieving better social functioning and quality of life.
Trial Details
NCT Number NCT06978803
Lead Sponsor Douglas Mental Health University Institute
Conditions
(from sponsor)
Psychosis, Schizophrenia Disorders
Related terms Motor Activity, Psychotic Disorders, Schizophrenia
Enrollment 110 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov