The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia

Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing self-harm. Carbamazepine (CBZ) is the first-line medication for TN, yet it presents adverse effects such as addiction and the absence of analgesic effects upon cessation. Acupuncture, particularly electroacupuncture（EA）, has demonstrated efficacy in TN treatment, although its therapeutic outcomes are influenced by various factors. Consequently, this study aims to evaluate the clinical efficacy of EA for TN and its potential as an alternative to CBZ treatment.

NCT Number	NCT06977932
Lead Sponsor	Yuanyuan Wu Collaborators: Pingyang County Traditional Chinese Medicine Hospital, Jiaxing Hospital of Traditional Chinese Medicine
Conditions	Trigeminal Neuralgia
Enrollment	126 participants
Start Date	2026-03-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2028-12-31 (estimated)
Updated on ClinicalTrials.gov	2026-03-05