Muscle Oxygen Saturation and Functional Capacity in Breast Cancer Survivors

This cross-sectional observational study aims to assess muscle oxygen saturation (SmO2) in the intercostal, quadriceps, and triceps surae muscles using near-infrared spectroscopy (NIRS) during functional exercise tests in breast cancer survivors. Participants will be grouped based on their previous cancer treatment: hormonal therapy only or hormonal therapy combined with chemotherapy. Functional performance will be evaluated through the 6-Minute Walk Test, 30-Second Sit-to-Stand Test, and a submaximal treadmill test. The study will analyze differences in muscle oxygenation and performance between groups and explore associations with other functional and clinical parameters.

NCT Number	NCT06976593
Lead Sponsor	University of Extremadura
Conditions	Breast Cancer Survivorship, Muscle Oxygenation, Near-infrared Spectroscopy, Exercise, Quality of Life, Functional Capacity, Hormonal Therapy
Enrollment	30 participants
Start Date	2025-05-05
Primary Completion	2025-05-31 (estimated)
Study Completion	2025-05-31 (estimated)
Updated on ClinicalTrials.gov	2025-05-16