Clinical Trial

Symptoms, Pulmonary Function, Muscle Strength, Exercise Capacity, and Frailty in Esophageal Atresia vs. Healthy Peers

Recruiting
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Summary
Esophageal atresia is the most common congenital anomaly of the esophagus and is caused by abnormal development of the esophagus during intrauterine life. In children with esophageal atresia, structural abnormalities due to congenital anomalies and tracheoesophageal fistula, tracheomalacia, respiratory problems, recurrent respiratory tract infections, structural abnormalities, surgical interventions for repair and treatment, and decreased physical activity levels may negatively affect pulmonary function, effective coughing, muscle strength, exercise capacity, posture, motor function, and quality of life. This study aims to compare physical characteristics, body composition, pulmonary function and muscle strength, peak cough flow, posture assessment, peripheral muscle strength test, motor function, exercise capacity, physical activity level, fatigue, frailty and quality of life between children with esophageal atresia and their healthy peers.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-05-09.
Trial Details
NCT Number NCT06975982
Lead Sponsor Hacettepe University
Conditions Esophageal Atresia, Healthy Children
Enrollment 20 participants
Start Date 2024-10-24
Primary Completion 2027-10-24 (estimated)
Study Completion 2027-10-24 (estimated)
Updated on ClinicalTrials.gov 2025-05-29