Clinical Trial

Community-Empowerment and Environmental Enrichment-based Co-management (CEEEC) Model and Mechanisms for Improving Health of Older Stroke Patients With Multimorbidity

Study acronym: CEEEC

Active, Not Recruiting

Record status

This record was last updated January 21, 2026 (before its estimated June 20, 2026 completion). Its status may not reflect the trial's current state.

Summary

This study is a cluster randomized controlled trial with a 2×2 factorial design conducted in community health centers in Kunshan, Harbin, Wuhan, Beijing and Shanghai. It aims to evaluate the independent and combined effects of exercise and cognitive interventions on intrinsic capacity and related health outcomes among stroke survivors aged 60 years and older with hypertension or type 2 diabetes mellitus. Participants will receive either exercise training, cognitive training, combined training, or usual care over 12 months, followed by a 12-month follow-up. Findings will inform integrated health management strategies for older adults with multimorbidity.

Protocol Amendment History 2 amendments

This ClinicalTrials.gov record has been amended 2 times since 2025-05-13; most recent amendment 2026-01-19.

Status change: Not Yet Recruiting → Active, Not Recruiting 2026-01-19

Trial Details

NCT Number	NCT06975501
Lead Sponsor	Duke Kunshan University Collaborators: Wuhan University, Harbin Medical University, Shanghai Jiao Tong University School of Medicine, Beijing Tiantan Hospital
Conditions	Hypertension, Type 2 Diabetes Mellitus (T2DM), Multimorbidity, Stroke
Enrollment	444 participants
Start Date	2025-06-20
Primary Completion	2026-06-20 (estimated)
Study Completion	2027-06-20 (estimated)
Updated on ClinicalTrials.gov	2026-01-21