Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

What if midlife women, who are inherently at an increased risk for future cardiometabolic disease due to transitioning into menopause, had access to a suite of evidence-based health interventions? Could these interventions reduce menopause-related inflammation, restore a healthier cardiometabolic profile, reverse epigenetic aging, and reduce bothersome menopausal symptoms? The ultimate goal of this work is to attenuate future disease and enhance women's quality of life, extend healthspan and increase productivity.

NCT Number	NCT06975111
Lead Sponsor	University of Colorado, Denver
Conditions	Menopause, Menopause Hot Flashes, Menopause Related Conditions, Cardiovascular
Enrollment	200 participants
Start Date	2026-03-01
Primary Completion	2029-10-31 (estimated)
Study Completion	2030-10-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-21